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Comparison of Mesenchymal Stem Cell Attachment Efficiency in Acellular Neural Graft for Peripheral Nerve Regeneration

1 month ago   |   By Journal of Plastic, Reconstructive & Aesthetic Surgery

Decellularized nerve allograft is an alternative to autologous nerve graft for nerve defects but has shown inferior clinical outcomes. Mesenchymal stem cells can play a key role in improving nerve regeneration of decellularized nerve allografts. The purpose of this study was to compare different mesenchymal stem cell seeding methods and find the most efficient way to attach cells to nerve grafts for peripheral nerve regeneration. Wharton's jelly mesenchymal stem cells were collected from human umbilical cords and were seeded in the acellular nerve graft in five different ways, as follows...
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