Senior

VIDEO: Examining adjuvant chemotherapy in locally advanced cervical cancer

11 days ago   |   By Healio

In this video, Christina M. Annunziata, MD, PhD, senior investigator at the National Cancer Institute, discussed the “practice-changing” results from the OUTBACK trial.
Researchers designed the international, randomized, phase 3 trial, which was presented during a plenary session at the ASCO Annual Meeting, to evaluate the potential survival benefit of adjuvant chemotherapy given after standard chemoradiation compared with chemoradiation alone in patients with locally advanced cervical cancer.
After 5 years, the data showed no difference in progression-free survival between the two
Read more ...

 

VIDEO: Study evaluates adjuvant bevacizumab duration in ovarian cancer

VIDEO: Study evaluates adjuvant bevacizumab duration in ovarian cancer

11 days ago   |   By Healio

In this video, Christina M. Annunziata, MD, PhD, senior investigator at the National Cancer Institute, spoke with Healio about findings from a study examining survival with longer vs. shorter duration of bevacizumab therapy in patients with advanced ovarian cancer.
For the study, the researchers randomly assigned patients to receive adjuvant bevacizumab for 15 or 30 months.
Both regimens were generally well tolerated, Annunziata noted, but OS was “essentially the same” between treatment arms.
“The conclusion from this study is that 15 months of bevacizumab
Read more ...

 

VIDEO: Less intense follow-up adequate in endometrial cancer

VIDEO: Less intense follow-up adequate in endometrial cancer

11 days ago   |   By Healio

In this video, Christina M. Annunziata, MD, PhD, senior investigator at the National Cancer Institute, discussed results from the TOTEM trial presented at the ASCO Annual Meeting.
Researchers designed TOTEM to compare intensive follow-up with minimalist follow-up in patients who were surgically treated for endometrial cancer and were in complete clinical remission. They stratified patients according to whether they had a low or high risk for recurrence and then randomly assigned patients to intensive or minimalist follow-up regimens.
In both high- and low-risk patients, intensive follow-up did
Read more ...

 


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Cholangiopathy after severe COVID-19 may lead to liver injury, failure

Cholangiopathy after severe COVID-19 may lead to liver injury, failure

For patients with severe COVID-19, cholangiopathy was a late complication with potential for progressive biliary injury or liver failure, according to a study published in the... Read more ...

Mississippi woman pleads others to get vaccinated as her husband is hospitalized

Mississippi woman pleads others to get vaccinated as her husband is hospitalized

William Thomas Ball, 51, has been hospitalized with COVID-19 in Jackson, Mississippi after refusing to get vaccinated. Now his wife, Alicia, is asking for others in her... Read more ...

Covid England: Cases are now falling in ALL age groups, official data reveals

Covid England: Cases are now falling in ALL age groups, official data reveals

EXCLUSIVE: Covid cases are falling in all age groups, and dropping fastest among adults in their twenties according to data from the Department of Health. Read more ...

Lumbar artificial disc yielded positive 7-year outcomes for degenerative...

Lumbar artificial disc yielded positive 7-year outcomes for degenerative disc disease

For total disc replacement in patients with degenerative disc disease, an artificial disc is a safe option that improves pain relief, function, range of motion and decreases in... Read more ...

FDA clamps down on imported shark fins, cantaloupes, mushrooms and more

FDA clamps down on imported shark fins, cantaloupes, mushrooms and more

The Food and Drug Administration uses import alerts to enforce U.S. food safety regulations for food from foreign countries. The agency updates and modifies the alerts as... Read more ...

FDA TechTalk podcast episode to focus on whole genome sequencing

FDA TechTalk podcast episode to focus on whole genome sequencing

Nowadays, it seems rare to find someone or some entity without a podcast, and the Food and Drug Administration is no exception. The TechTalk podcast is hosted by the FDA and... Read more ...

COVID Breakthrough Cases Ran the Gamut in Healthcare Workers

COVID Breakthrough Cases Ran the Gamut in Healthcare Workers

Breakthrough COVID-19 cases in fully vaccinated healthcare workers were rare, and generally were associated with the individual's immune response to the vaccine in the early... Read more ...

Some IBD Treatments in Pregnancy Had No Effect on Kids' Infection Risk

Some IBD Treatments in Pregnancy Had No Effect on Kids' Infection Risk

Exposure to immunosuppressive monotherapies in utero did not increase serious infection risks in young children born to mothers with inflammatory bowel disease , but the same... Read more ...

FDA issues complete response letter for retifanlimab for anal cancer

FDA issues complete response letter for retifanlimab for anal cancer

The FDA issued a complete response letter to Incyte indicating it cannot approve the company's biologics license application that seeks approval of retifanlimab for certain... Read more ...

Bristol Myers Squibb withdraws liver cancer indication for nivolumab

Bristol Myers Squibb withdraws liver cancer indication for nivolumab

Bristol Myers Squibb in consultation with the FDA voluntarily withdrew the indication for nivolumab as monotherapy for patients with hepatocellular carcinoma previously treated... Read more ...