AIDS

Patients on failing HIV regimens achieve viral suppression with long-acting lenacapavir

11 days ago   |   By Healio

Researchers at the International AIDS Society Conference on HIV Science reported more promising data on lenacapavir, the investigational, long-acting HIV-1 capsid inhibitor that is administered subcutaneously every 6 months.
Data from an ongoing phase 2/3 study of heavily treatment-experienced people with multidrug-resistant HIV showed that 81% of participants who received lenacapavir in combination with an optimized background regimen achieved sustained virologic suppression at week 26.
Gilead Sciences submitted a new drug application to the FDA earlier this month seeking approval for
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Toward one drug to treat all coronaviruses

Toward one drug to treat all coronaviruses

11 days ago   |   By ScienceDaily

Researchers have analyzed viral proteins across 27 coronavirus species and thousands of samples from COVID-19 patients, identifying highly conserved sequences that could make the best drug targets.
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Novel Drug Helped HIV Patients Achieve Viral Suppression

Novel Drug Helped HIV Patients Achieve Viral Suppression

11 days ago   |   By MedPageToday

More than 80% of heavily treatment-experienced HIV patients with multi-drug resistance who received long-acting subcutaneous lenacapavir along with an optimized background regimen experienced viral suppression at week 26, according...
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Cholangiopathy after severe COVID-19 may lead to liver injury, failure

Cholangiopathy after severe COVID-19 may lead to liver injury, failure

For patients with severe COVID-19, cholangiopathy was a late complication with potential for progressive biliary injury or liver failure, according to a study published in the... Read more ...

Mississippi woman pleads others to get vaccinated as her husband is hospitalized

Mississippi woman pleads others to get vaccinated as her husband is hospitalized

William Thomas Ball, 51, has been hospitalized with COVID-19 in Jackson, Mississippi after refusing to get vaccinated. Now his wife, Alicia, is asking for others in her... Read more ...

Covid England: Cases are now falling in ALL age groups, official data reveals

Covid England: Cases are now falling in ALL age groups, official data reveals

EXCLUSIVE: Covid cases are falling in all age groups, and dropping fastest among adults in their twenties according to data from the Department of Health. Read more ...

Lumbar artificial disc yielded positive 7-year outcomes for degenerative...

Lumbar artificial disc yielded positive 7-year outcomes for degenerative disc disease

For total disc replacement in patients with degenerative disc disease, an artificial disc is a safe option that improves pain relief, function, range of motion and decreases in... Read more ...

FDA clamps down on imported shark fins, cantaloupes, mushrooms and more

FDA clamps down on imported shark fins, cantaloupes, mushrooms and more

The Food and Drug Administration uses import alerts to enforce U.S. food safety regulations for food from foreign countries. The agency updates and modifies the alerts as... Read more ...

FDA TechTalk podcast episode to focus on whole genome sequencing

FDA TechTalk podcast episode to focus on whole genome sequencing

Nowadays, it seems rare to find someone or some entity without a podcast, and the Food and Drug Administration is no exception. The TechTalk podcast is hosted by the FDA and... Read more ...

COVID Breakthrough Cases Ran the Gamut in Healthcare Workers

COVID Breakthrough Cases Ran the Gamut in Healthcare Workers

Breakthrough COVID-19 cases in fully vaccinated healthcare workers were rare, and generally were associated with the individual's immune response to the vaccine in the early... Read more ...

Some IBD Treatments in Pregnancy Had No Effect on Kids' Infection Risk

Some IBD Treatments in Pregnancy Had No Effect on Kids' Infection Risk

Exposure to immunosuppressive monotherapies in utero did not increase serious infection risks in young children born to mothers with inflammatory bowel disease , but the same... Read more ...

FDA issues complete response letter for retifanlimab for anal cancer

FDA issues complete response letter for retifanlimab for anal cancer

The FDA issued a complete response letter to Incyte indicating it cannot approve the company's biologics license application that seeks approval of retifanlimab for certain... Read more ...

Bristol Myers Squibb withdraws liver cancer indication for nivolumab

Bristol Myers Squibb withdraws liver cancer indication for nivolumab

Bristol Myers Squibb in consultation with the FDA voluntarily withdrew the indication for nivolumab as monotherapy for patients with hepatocellular carcinoma previously treated... Read more ...