Hospital

Antipyretic Efficacy of Acetaminophen and Ibuprofen in Critically Ill Pediatric Patients

5 days ago   |   By Pediatric Critical Care Medicine

Objectives:
To determine the antipyretic efficacy of acetaminophen and ibuprofen in critically ill febrile pediatric patients.
Design:
Retrospective cohort study.
Setting:
Quaternary care pediatric hospital ICUs.
Patients:
Pediatric patients less than 19 years old who were febrile , received a dose of IV acetaminophen, enteral acetaminophen, rectal acetaminophen, or enteral ibuprofen and had at least one temperature measurement in the following 6 hours.
Interventions:
None.
Measurements and Main Results:
A total of 3,341 patients (55.8% male, median age 2.5 yr ) met study criteria...
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