SARS-CoV-2 variants emerge during humoral immunity phase of acute COVID-19

12 days ago   |   By News Medical

A new preprint research paper posted to the bioRxiv server reports the rapid emergence of variants within an infected individual. The evolution of the virus within an infected host is not excluded by the close similarity between the consensus sequences of single-person SARS-CoV-2, since the number of viral copies is at its peak soon after infection occurs and before the host develops adaptive immunity.
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Research predicts which mammal species can spread SARS-CoV-2

12 days ago   |   By News Medical

Scientists worldwide are fighting to contain the ongoing COVID-19 pandemic, which has already claimed more than 2.48 million lives. Preventing spillback infections is essential to containing the pandemic. To do so, it is vital to understand the nature of the virus, i.e., its susceptibility to a range of hosts.
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Key mutation sites in the SARS-CoV-2 spike protein modulate antibody and ACE2 affinity

12 days ago   |   By News Medical

A paper recently uploaded to the preprint server bioRxiv by researchers at Chapman University in California utilized computational methods to screen severe acute respiratory syndrome coronavirus 2 mutants for affinity with the angiotensin-converting enzyme 2 receptor and monoclonal antibodies REG10987 and REG10933.
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SARS-CoV-2 mutations allow escape from clinical monoclonal antibodies

12 days ago   |   By News Medical

A new research paper recently uploaded to the preprint server bioRxiv by Jesse D. Bloom et al. aims to map all of the currently circulating SARS-CoV-2 lineages with resistance towards LY-CoV555 and LY-CoV016, and document the specific mutations that confer resistance, ultimately suggesting that future monoclonal antibody cocktails should target a more diverse range of epitopes.
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GSK-3 inhibitors show promise in treating coronavirus infections

12 days ago   |   By News Medical

Researchers in the United States have suggested a new approach to treating infection with coronaviruses such as severe acute respiratory syndrome coronavirus 2 - the agent that causes coronavirus disease 2019 .
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Glycan switch may explain why SARS-CoV-2 causes such variable symptoms

12 days ago   |   By News Medical

Researchers in Portugal have provided evidence that might explain why infection with severe acute respiratory syndrome coronavirus 2 causes mild or even asymptomatic illness in some individuals, but severe coronavirus disease 2019 in others.
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FMG confirms 380 jobs impacted as Iron Bridge cost blowout hits contractors

FMG CEO Elizabeth Gaines said the company was working closely with contractors to support redeployment to other Fortescue sites where possible. Read more ...

Liberatore shrugs off concerns about interchange rule

Premiership Western Bulldog Tom Liberatore has shrugged off concerns about the AFL's new interchange rule, saying the Bulldogs have the midfield depth to combat fatigue in... Read more ...

Missing patient with Brazilian Covid strain is FOUND after nationwide hunt 

Missing patient with Brazilian Covid strain is FOUND after nationwide hunt 

To date, six cases of the variant of concern have been found in the UK - three in Scotland and three in England. A public appeal had been made for one of those people in... Read more ...

Tour of South Africa to be rescheduled ‘as soon as possible': Hockley

The interim Cricket Australia chief executive does not want the dispute with Cricket South Africa to reach ICC level. Read more ...

‘A slippery slope': Dragons question ‘scary' NRL stance on Norman brawl

Corey Norman's teammates have expressed about becoming public targets after the NRL rejected a self-defence argument from the Dragon about his involvement in a street fight. Read more ...

Houli expected to miss, star Blues recruit suspended, Roos star hurt

Richmond is expected to be without all-Australian defender Bachar Houli against the Blues, who have a series of selection posers ahead of the season-opener. North Melbourne's... Read more ...

Debate welcome, but no immediate plans to drop ‘W' from BBL: Hockley

Interim Cricket Australia chief executive Nick Hockley has responded to the call from World Cup winner Meg Lanning to change the name of the women's T20 tournament. Read more ...

Rodda to take massive pay cut - and spurn Waratahs - to come home

The Wallabies lock will sacrifice as much as $700,000 to return to Australian rugby in 2022, and, in a shock twist, is set to knock back NSW and sign for the Force. Read more ...

Coronavirus UK: Britain's daily Covid cases drop to 5,947 and deaths fall by...

Coronavirus UK: Britain's daily Covid cases drop to 5,947 and deaths fall by a third

The latest infection figures, released late this evening by Public Health England, show a thirty per cent drop week-on-week compared to last Friday, when more than 8,500 cases... Read more ...

Coronavirus: UK care home visitors urged to get a Covid vaccine as soon as...

Coronavirus: UK care home visitors urged to get a Covid vaccine as soon as possible

Updated guidance from the Department of Health said that people who wanted to visit care homes in England should take up the offer of a Covid vaccine as soon as they are... Read more ...