Lefamulin safe, effective monotherapy alternative for older adults with CABP

4 days ago   |   By Healio

Lefamulin demonstrated high early clinical response and was safe in patients with community-acquired bacterial pneumonia with advanced age and comorbidities, according to a post hoc, pooled analysis of the LEAP 1 and LEAP 2 trials.
Lefamulin is a first-in-class pleuromutilin antibiotic that is FDA approved for IV and oral use in adults with community-acquired bacterial pneumonia. Efficacy and safety of lefamulin were previously demonstrated in the noninferiority phase 3 LEAP 1 and LEAP 2 trials. At the virtual CHEST Annual Meeting, researchers reported
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