Diabetes

Sentinel lymph node biopsy may help guide treatment decisions in stage II melanoma

2 monthes ago   |   By Healio

Sentinel lymph node biopsy was effective as a prognostic and staging tool in stage IIB/C melanoma, according to a study.
“Pembrolizumab , an antibody against programmed cell death receptor 1 , was recently approved as an adjuvant therapy for patients with high risk clinically localized advanced melanoma at clinical stage IIB/C,” Cimarron E. Sharon, MD, of the department of surgery at the University of Pennsylvania, Perelman School of Medicine, Philadelphia, told Healio. “This is significant because this is the first modern adjuvant therapy to be
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Novel GIP receptor antagonist/GLP-1 receptor agonist for obesity safe in phase 1 trial

Novel GIP receptor antagonist/GLP-1 receptor agonist for obesity safe in phase 1 trial

2 monthes ago   |   By Healio

A novel bispecific GIP receptor antagonist and GLP-1 receptor agonist induced weight loss of up to 14.5% in adults with obesity with no safety concerns, according to data from a phase 1 trial.
In findings presented at the World Congress on Insulin Resistance, Diabetes & Cardiovascular Disease, nearly all treatment-emergent adverse events reported among adults with obesity receiving either single or multiple doses of AMG 133 were mild in nature. The agent also induced significantly greater weight loss in participants receiving a single dose and multiple doses compared with those
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Study reveals some of the fundamental biology of p97 protein in...

The p97 protein is one of your body's best garbage disposers. It floats around in your cells looking for signals that a protein is past its shelf life and needs to be trashed. Read more ...

Newborn baby found in rubble as death tolls rises from earthquake

Rescuers continue to search for survivors trapped under collapsed buildings as the death toll rises from the powerful earthquake in Turkey and Syria. A newborn baby was among... Read more ...

Endoscopic procedure may be safe, successful treatment for lumbar spondylolysis

Endoscopic procedure may be safe, successful treatment for lumbar spondylolysis

Published results showed interlaminar percutaneous endoscopic pars decompression may be safe and successful among patients with stable lumbar spondylolysis and nerve root... Read more ...

Scientists discover new way to reduce progression of diabetic kidney disease

A new way to reduce progression of diabetic kidney disease, affecting 40% of people with diabetes, has been discovered by scientists. Read more ...

The worrying trend of Victoria's ‘under-vaccinated' filling COVID wards

Frontline Melbourne clinicians say many of the elderly COVID patients they are now treating were vaccinated, but haven't had a booster shot recently. Read more ...

UC researcher aims to develop better treatments for KRAS-mutated pancreatic...

Pancreatic cancer diagnoses are increasing more rapidly than any other cancer type while remaining one of the most deadly cancers. Read more ...

Do individuals with long COVID ever recover fully?

Researchers investigate the sociodemographic factors that contribute to the remission of long COVID. Read more ...

Hundreds of ‘priceless' orchids poached from Perth's Kings Park

Close to 1000 plants were stolen from Kings Park in Perth, leaving those who work there “devastated.” Read more ...

Aussie family injured after holiday home in New Zealand collapses

An Aussie family has been injured after their holiday home in New Zealand collapsed. Read more ...

AI can be a powerful tool to help identify lung nodules on chest X-rays

In a pioneering, randomized controlled study evaluating the effect of artificial intelligence -based software in real clinical practice, researchers found that AI significantly... Read more ...