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Active Cellular Immunotherapy Disappoints in Metastatic Prostate Cancer

7 monthes ago   |   By MedPage Today

An autologous dendritic cell-based immunotherapy added to chemotherapy did not improve survival in patients with metastatic castration-resistant prostate cancer , a phase III trial found.
Among over 1,100...
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Enzalutamide Rechallenge Yields Small PFS Boost in Metastatic Prostate Cancer

Enzalutamide Rechallenge Yields Small PFS Boost in Metastatic Prostate Cancer

7 monthes ago   |   By MedPage Today

In patients with metastatic castration-resistant prostate cancer who have progressed on enzalutamide , those who continued the treatment in combination with docetaxel and prednisolone saw improved progression-free...
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A potential way for overcoming immunotherapy resistance in patients with mucosal melanomas

A potential way for overcoming immunotherapy resistance in patients with mucosal melanomas

7 monthes ago   |   By News Medical

The development of the anti-cancer immunotherapy drugs called immune checkpoint inhibitors has improved treatment for many cancer patients, but patients with mucosal melanomas -; melanomas that occur not on the skin but in the mucous membranes in the head, neck, eyes, respiratory tract, and genitourinary region -; are particularly resistant to immune checkpoint inhibitors for reasons researchers don't fully understand.
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VIDEO: Visual acuity in wet AMD maintained or improved after switch to...

VIDEO: Visual acuity in wet AMD maintained or improved after switch to brolucizumab

In this Healio Video Perspective, Mathew W. MacCumber, MD, PhD, discusses his poster presentation on brolucizumab treatment from the Retina Society meeting. The real-world... Read more ...

Small-aperture IOL a ‘must-have' technology for cataract surgeons

Small-aperture IOL a ‘must-have' technology for cataract surgeons

NEW YORK - Small-aperture IOLs are an important tool for managing patients with challenging eyes, according to an expert at OSN New York. Eric D. Donnenfeld, MD, said... Read more ...

Albuminuria Remission With Meds; Tzield's High Cost; Osteoporosis Prevention...

Albuminuria Remission With Meds; Tzield's High Cost; Osteoporosis Prevention Lags

"Best" medical treatment with drugs such as SGLT2 inhibitors and GLP-1 receptor agonists was just as effective as Roux-en-Y gastric bypass at achieving albuminuria remission in... Read more ...

Corticosteroid injections associated with progression of knee osteoarthritis

Two studies comparing injections commonly used to relieve the pain of knee osteoarthritis found that corticosteroid injections were associated with the progression of the disease. Read more ...

An unexplained injury discovered after eye surgery. What should happen next?

When Jerry Bilinski, a 67-year-old retired social worker, scheduled cataract surgery with Carolina Eye Associates near his home in Fayetteville, North Carolina, he expected no... Read more ...

Denosumab achieves structural modification in erosive hand osteoarthritis

Denosumab achieves structural modification in erosive hand osteoarthritis

PHILADELPHIA - Denosumab successfully induces structural modifications patients with active erosive hand osteoarthritis, according to data presented at ACR Convergence... Read more ...

Is Surgery the Only Option for Meniscal Tear and Osteoarthritis?

New research finds that for some patients, physical therapy provides similar improvements in physical function and pain. Read more ...

Caddick inquest told of lengthy delays in reviewing CCTV, analysing DNA

A senior officer blamed staff shortages and lack of resources for the delays, the inquest into the Sydney fraudster's disappearance and presumed death has heard. Read more ...

GPs fail to identify osteoporosis sparking fears of a hidden epidemic of...

GPs fail to identify osteoporosis sparking fears of a hidden epidemic of brittle bones

Family doctors are well placed to diagnose and treat osteoporosis - which causes brittle bones - but too many people are diagnosed only after a fall, the cross-party group of... Read more ...

Racial, ethnic minorities underrepresented in prostate cancer clinical trials

Racial, ethnic minorities underrepresented in prostate cancer clinical trials

Prostate cancer clinical trials included significant underrepresentation of Asian, Black and Hispanic men based on incidence of the disease among these groups, results of... Read more ...