Tumors

Pathological response to neoadjuvant therapy correlates to RFS, OS in stage III melanoma

8 days ago   |   By Healio

Pathological response should be an early surrogate endpoint for clinical trials of neoadjuvant therapy for melanoma, according to results of a pooled analysis published in Nature Medicine.
Pathological complete response also should be a new benchmark for drug development and approval, study authors concluded.
“Neoadjuvant systemic therapy has the potential to reduce tumor burden to facilitate and likely reduce the extent of surgical resection for stage III melanoma, as well as provide prognostic information to allow personalized follow-up and alternative adjuvant therapy in
Read more ...

 


Search by Tags

   Tumors      Drugs  


Antibodies Deplete Cancer Cells in Mice and Human Cell Lines

Antibodies Deplete Cancer Cells in Mice and Human Cell Lines

New studies reveal the promise of engineered bispecific antibodies by demonstrating their power against previously inaccessible tumor cell targets for the first time. Read more ...

Modifying Alpha Cells into Beta Cells Helps Treat Diabetes

Modifying Alpha Cells into Beta Cells Helps Treat Diabetes

Antibodies that convert glucagon-producing cells into insulin-producing ones cure mouse models of the diabetes. Read more ...

Caramelized Onion and Pear Fruit Frittata

Caramelized Onion and Pear Fruit Frittata

This Caramelized Onion and Pear Fruit Frittata combines the sweet and savory flavors of sweet caramelized onion, pear, and protein-rich eggs. How often do you sit down to eat... Read more ...

‘Not a good look': Push grows for JobKeeper payments to be returned as...

A raft of high-profile Australian businesses have been slammed by economists, investors and politicians over their decision to pocket millions in JobKeeper subsidies. Read more ...

Race-by-race tips and preview for Warwick Farm on Wednesday

Everything you need to know to pick a winner on an eight-race card. Read more ...

O'Shea keen to make up for lost time as gelding gets back up and running

Lost And Running has had knee surgery since scoring his second runaway win back in June, but his trainer says the gelding is in A1 shape following two barrier trial wins. Read more ...

China's deputy ambassador warns ‘it's now a sin to be a friend of China'

Wang Xining said Australia's children will be ashamed of those who sabotaged the friendship with China and urged business leaders to reset the relationship. Read more ...

‘They forced medication on me': Patients back curbs on controversial treatments

People who have been subjected to compulsory treatment, seclusion and restraint have welcomed royal commission findings that such methods should be limited or scrapped. Read more ...

‘Have to pay somehow': Experts say wage levy for aged care won't be enough

Almost 10 million Australians could pay up to $610 a year if the government introduces a new 1 per cent income levy to fund aged care services. Read more ...

‘Ridiculous': Cambodian court sentences opposition leaders in absentia

Sam Rainsy, who was sentenced to 25 years, said the court acted at the behest of PM Hun Sen. Human rights organisations slammed the decision. Read more ...