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Pediatric tumor-sequencing trial finds higher rate of targetable alterations than expected

9 days ago   |   By Healio

Genetic sequencing of tumors among children with refractory cancer led to about a quarter of those tested being matched with therapies targeting their specific genetic alteration, according to results of a study scheduled for presentation at ASCO Annual Meeting.
Investigators in the Pediatric MATCH study from the NCI and Children's Oncology Group had projected only a 10% match rate.
“These data provide some preliminary insight for clinicians into the diagnostic yield of tumor molecular testing for children with refractory cancers in terms of probability of identifying a targeted
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