Brain

Traumatic Brain Injury in Children: Glial fibrillary Acidic Protein and Clinical Outcomes

3 days ago   |   By Pediatric Emergency Care

Objectives
Glial fibrillary acidic protein is a neuronal protein released after traumatic brain injury and detectable in serum samples. GFAP correlates with symptom severity in adults and may be a marker of brain injury in children with milder symptoms or preverbal children.
Methods
GFAP was examined in children with severe TBI (initial Glasgow Coma Scale score 1-point changes from their preinjury functioning on the Post-Concussive Symptom Inventory had higher initial GFAP but not total Post-Concussive Symptom Inventory score changes.
Conclusions
GFAP identifies children with TBI, even at...
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